treatment resistant Archives - Gateway Psychiatric Excellent Psychiatric Care Wed, 07 Jul 2021 13:20:03 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.1 https://i0.wp.com/www.gatewaypsychiatric.com/wp-content/uploads/2013/06/favicon2.png?fit=32%2C32&ssl=1 treatment resistant Archives - Gateway Psychiatric 32 32 70562394 How Long Does It Take to Get Well with TMS https://www.gatewaypsychiatric.com/how-long-does-it-take-to-get-well-with-tms/ https://www.gatewaypsychiatric.com/how-long-does-it-take-to-get-well-with-tms/#respond Sat, 20 Jul 2019 13:56:37 +0000 https://www.gatewaypsychiatric.com/?p=15753 The most common question that people ask when they start TMS is how long it will take to get well with TMS. A recent article published in the American Journal of Psychiatry looked at the results from a six week study designed to compare theta burst and regular TMS in order to assess patterns of response over time. The authors ...

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]]> https://www.gatewaypsychiatric.com/how-long-does-it-take-to-get-well-with-tms/feed/ 0 15753 Default Mode Network and Depression Treatment – Ketamine and TMS https://www.gatewaypsychiatric.com/default-mode-network-and-depression/ https://www.gatewaypsychiatric.com/default-mode-network-and-depression/#respond Tue, 02 May 2017 20:50:45 +0000 https://www.gatewaypsychiatric.com/?p=13186 Interaction between the default mode network and parts of the pre-frontal cortex may explain some depression phenomena and also links to why TMS and ketamine work

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]]> https://www.gatewaypsychiatric.com/default-mode-network-and-depression/feed/ 0 13186 Lithium and Genes https://www.gatewaypsychiatric.com/lithium-and-genes/ Sun, 14 Feb 2016 20:15:58 +0000 https://www.gatewaypsychiatric.com/?p=9993 Several studies have suggested that lithium response has a genetic component. Whether someone with bipolar will respond to treatment with lithium seems to be strongly associated with the presence or absence of a family history of response to the medication. A recent article in the Lancet reports the results of a genome-wide association study of lithium response in 2563 patients collected ...

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]]> 9993 Ketamine for Depression Update https://www.gatewaypsychiatric.com/ketamine-for-depression-update/ Sun, 04 Oct 2015 16:32:29 +0000 https://www.gatewaypsychiatric.com/?p=9261 Probably the most exciting development in psychopharmacology in years is the discovery of the dramatic effects of ketamine on depression. However, a recent report from the American Psychiatric Association (APA) Task Force on Novel Biomarkers and Treatments highlights not only the reason for the excitement about ketamine but also the significant areas of uncertainty that make it not yet ready to ...

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]]> 9261 Stimulants and Geriatric Depression https://www.gatewaypsychiatric.com/stimulants-and-geriatric-depression/ Sat, 28 Feb 2015 14:45:50 +0000 https://www.gatewaypsychiatric.com/?p=8901 Stimulants and Geriatric Depression May be Underused. A well designed study showed that adding methylphenidate (Ritalin and others) to citalopram (Celexa) improve the likelihood of complete remission from depression in older patients. In general older depressed patients are more likely to have some cognitive impairment and are less likely to respond to antidepressants. A number of reports suggests that adding stimulants to antidepressants can ...

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]]> 8901 Bipolar Depression https://www.gatewaypsychiatric.com/bipolar-depression/ Wed, 21 Jan 2015 22:00:00 +0000 https://www.gatewaypsychiatric.com/?p=8477 The recent presentation that I gave at UCSF on this topic allowed me to review all of the controlled clinical trials related to the treatment of bipolar depression. In a follow-up post I plan on talking about some of the exciting new developments that suggest that we will soon, and to some extent do already, have some very promising approaches ...

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]]> 8477 TMS Media – The Doctors https://www.gatewaypsychiatric.com/tms-media/ Sat, 06 Dec 2014 19:19:01 +0000 https://www.gatewaypsychiatric.com/?p=8413 TMS Media – “The Doctors” December 3 I am excited to share with you that on December 3rd “The Doctors” featured a segment on TMS. Todd Hutton, MD,  Medical Director, Southern California TMS Center, was invited to appear with a patient who is doing great 18 months post TMS treatment. I hope you can watch and that this contributes to further awareness ...

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]]> 8413 Anhedonia Treatment with Ketamine https://www.gatewaypsychiatric.com/anhedonia-treatment-ketamine/ Tue, 25 Nov 2014 14:15:18 +0000 https://www.gatewaypsychiatric.com/?p=8360 The treatment of anhedonia and bipolar depression can be very difficult. An article published in Translational Psychiatry in October of 2014 highlights the role of glutametergic transmission in anhedonia and points to the potentially unique efficacy of ketamine in treating this stubborn problem. Anhedonia, the lack (an-) of pleasure (-hedonia), is one of the 2 main symptoms of a major ...

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]]> 8360 Genetic Testing for Depression Drugs https://www.gatewaypsychiatric.com/genetic-testing-depression-drugs/ Sat, 11 Oct 2014 14:25:06 +0000 https://www.gatewaypsychiatric.com/?p=8225 Genetic testing for depression drugs is a new approach to selecting medications that may have value, especially in patients with treatment resistant depression. We have been using the Genecept Assay for patients with treatment resistant depression and have found that the results improve our ability to choose effective treatments. Patients who have failed multiple adequate trials of medications are much less likely to ...

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]]> 8225 Ketamine for Depression – Mechanism of Action https://www.gatewaypsychiatric.com/ketamine-depression-mechanism-action/ Sat, 04 Oct 2014 16:15:42 +0000 https://www.gatewaypsychiatric.com/?p=8187 Ketamine for Depression: How does it work? We ran across a useful review of the basic science literature in an interview of David Nichols on the Psych Congress Network. http://www.psychcongress.com/video/ketamine-quick-guide-receptors-19116 Although ketamine blocks the NMDA subtype of glutamate receptors (blocks an excitatory neurotransmitter) the net effect seems to be an increase in excitatory neurotransmission. This image from Nature may help ...

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