treatment response Archives - Gateway Psychiatric Excellent Psychiatric Care Wed, 07 Jul 2021 13:20:03 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://i0.wp.com/www.gatewaypsychiatric.com/wp-content/uploads/2013/06/favicon2.png?fit=32%2C32&ssl=1 treatment response Archives - Gateway Psychiatric 32 32 70562394 Predicting Lithium Response https://www.gatewaypsychiatric.com/predicting-lithium-response/ https://www.gatewaypsychiatric.com/predicting-lithium-response/#respond Tue, 19 Nov 2019 02:17:19 +0000 https://www.gatewaypsychiatric.com/?p=15909 Lithium is usually considered the most effective treatment for bipolar disorder. However, at least 30% of lithium-treated patients do not have a clinically significant response; and only 30% have a long-lasting full response. Since close laboratory monitoring is required, and adverse effects are not uncommon, identifying predictors of lithium response is highly desirable. In this largest-ever study of lithium recipients ...

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]]> https://www.gatewaypsychiatric.com/predicting-lithium-response/feed/ 0 15909 How Long Does It Take to Get Well with TMS https://www.gatewaypsychiatric.com/how-long-does-it-take-to-get-well-with-tms/ https://www.gatewaypsychiatric.com/how-long-does-it-take-to-get-well-with-tms/#respond Sat, 20 Jul 2019 13:56:37 +0000 https://www.gatewaypsychiatric.com/?p=15753 The most common question that people ask when they start TMS is how long it will take to get well with TMS. A recent article published in the American Journal of Psychiatry looked at the results from a six week study designed to compare theta burst and regular TMS in order to assess patterns of response over time. The authors ...

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]]> https://www.gatewaypsychiatric.com/how-long-does-it-take-to-get-well-with-tms/feed/ 0 15753 Predicting Lithium Response with Brain Imaging https://www.gatewaypsychiatric.com/predicting-lithium-response-brain-imaging/ https://www.gatewaypsychiatric.com/predicting-lithium-response-brain-imaging/#respond Thu, 12 Oct 2017 21:22:31 +0000 https://www.gatewaypsychiatric.com/?p=14796 Predicting lithium response with brain imaging may be an option in the future if the preliminary results of a study published in 2017 are confirmed. Researchers from the University of Cincinnati used three tools to create a program that was remarkably successful at predicting which bipolar patients would respond to lithium. 20 first onset bipolar patients who received adequate trials ...

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]]> https://www.gatewaypsychiatric.com/predicting-lithium-response-brain-imaging/feed/ 0 14796 Functional Brain Imaging in Depression https://www.gatewaypsychiatric.com/functional-brain-imaging-depression/ Mon, 15 May 2017 08:14:22 +0000 https://www.gatewaypsychiatric.com/?p=12993 Is there a role for functional brain imaging in depression? Many people seeking treatment are interested in the notion that the brain imaging, particularly imaging that looks at neural activity, might be useful in guiding treatment. Up until the last couple of years the answer to this question has always been that the role is primarily restricted to research settings ...

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]]> 12993 Atypical Antipsychotics with Mood Stabilizers https://www.gatewaypsychiatric.com/atypical-antipsychotics-with-mood-stabilizers/ Sun, 22 Jan 2017 18:42:37 +0000 https://www.gatewaypsychiatric.com/?p=12223 Many people with bipolar receive atypical antipsychotics with mood stabilizers. As in many areas of medicine, we have relatively little data about longer-term outcomes when people receive this combination. If an atypical antipsychotic is added to a mood stabilizer to control a manic episode, how long should that combination be prescribed? A recent study conducted by the Canadian Mood and ...

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]]> 12223 Antidepressant Response Linked to Norepinephrine Transporter Genotype https://www.gatewaypsychiatric.com/antidepressant-response-linked-norepinephrine-transporter-genotype/ Sun, 15 Jan 2017 03:06:41 +0000 https://www.gatewaypsychiatric.com/?p=12213 A large study of patients treated with venlafaxine found that antidepressant response was linked to the norepinephrine transporter (NET) genotype. The study looked at response in a sample of 350 individuals over the age of 60 with severe depression (MADRS greater than or equal to 15) who were treated with venlafaxine up to a dose of 300 mg a day. ...

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]]> 12213 Antidepressants Alter Gene Expression https://www.gatewaypsychiatric.com/antidepressants-alter-gene-expression/ Fri, 22 Jul 2016 20:55:51 +0000 https://www.gatewaypsychiatric.com/?p=11225 An interesting study looked at similarities and differences in the effects of two medications that have anti-depressant effects and yet are extremely different in terms of how they work: ketamine and imipramine (a tricyclic antidepressant). This industry supported study looked at the effects of these two agents on a reward circuit (involving the prefrontal cortex (PFC), nucleus accumbens, hippocampus, and amygdala – ...

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]]> 11225 Lithium and Genes https://www.gatewaypsychiatric.com/lithium-and-genes/ Sun, 14 Feb 2016 20:15:58 +0000 https://www.gatewaypsychiatric.com/?p=9993 Several studies have suggested that lithium response has a genetic component. Whether someone with bipolar will respond to treatment with lithium seems to be strongly associated with the presence or absence of a family history of response to the medication. A recent article in the Lancet reports the results of a genome-wide association study of lithium response in 2563 patients collected ...

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]]> 9993 Functional Brain Imaging and Antidepressant Response https://www.gatewaypsychiatric.com/functional-brain-imaging-and-antidepressant-response/ Wed, 10 Feb 2016 04:33:45 +0000 https://www.gatewaypsychiatric.com/?p=10053 One of the most exciting initiatives currently in the important area of  the treatment of depression is the International Study to Predict Optimized Treatment in Depression (iSPOT-D). This large multi-center initiative is based on a private industry and academic partnership that is designed to both identify best practices in the treatment of depression and also commercialize them. The most recent publication from this ...

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]]> 10053 ABCB1 Gene Predicts Antidepressant Response https://www.gatewaypsychiatric.com/abcb1-predicts-antidepressant-response/ Tue, 31 Mar 2015 03:42:01 +0000 https://www.gatewaypsychiatric.com/?p=8970 An article that will soon appear in the American Journal of Psychiatry suggests that it may be possible to predict who will respond to different antidepressants using a genetic test. The study looked at whether by testing for specific genetic variants of a protein involved in transporting drugs and other potentially toxic substances into and out of cells and across the blood ...

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