treatment selection Archives - Gateway Psychiatric Excellent Psychiatric Care Tue, 06 Jul 2021 21:43:13 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.4 https://i0.wp.com/www.gatewaypsychiatric.com/wp-content/uploads/2013/06/favicon2.png?fit=32%2C32&ssl=1 treatment selection Archives - Gateway Psychiatric 32 32 70562394 Limbic and Prefrontal Connectivity and Treatment Selection for Depression https://www.gatewaypsychiatric.com/limbic-and-prefrontal-connectivity-and-treatment-selection-for-depression/ Thu, 27 Aug 2020 02:00:00 +0000 https://www.gatewaypsychiatric.com/?p=12607 Boadie Dunlop, M.D., M.S., and Helen Mayberg, M.D., both of Emory University School of Medicine, and colleagues assessed resting-state functional connectivity between the subcallosal cingulate cortex (SCC) and three other brain regions—the dorsal midbrain, the ventrolateral prefrontal cortex and anterior insula, and the ventromedial prefrontal cortex—in 122 patients with depression. The patients were then randomized to 12 weeks of cognitive-behavioral ...

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]]> 12607 Predicting Lithium Response https://www.gatewaypsychiatric.com/predicting-lithium-response/ https://www.gatewaypsychiatric.com/predicting-lithium-response/#respond Tue, 19 Nov 2019 02:17:19 +0000 https://www.gatewaypsychiatric.com/?p=15909 Lithium is usually considered the most effective treatment for bipolar disorder. However, at least 30% of lithium-treated patients do not have a clinically significant response; and only 30% have a long-lasting full response. Since close laboratory monitoring is required, and adverse effects are not uncommon, identifying predictors of lithium response is highly desirable. In this largest-ever study of lithium recipients ...

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]]> https://www.gatewaypsychiatric.com/predicting-lithium-response/feed/ 0 15909 Genetic Tests for Antidepressants – CNS Dose https://www.gatewaypsychiatric.com/genetic-tests-for-antidepressants-cns-dose/ https://www.gatewaypsychiatric.com/genetic-tests-for-antidepressants-cns-dose/#respond Mon, 10 Jul 2017 02:25:56 +0000 https://www.gatewaypsychiatric.com/?p=14344 About a year ago we reviewed the data on the use of genetic tests for antidepressants as well as other medications and identified three pharmacogenetic panels that seem to have research support: Genecept by Genomind, Genesight, and CNS Dose. Of these three we have been using Genecept and Genesight with some success but now we are happy to add to ...

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]]> https://www.gatewaypsychiatric.com/genetic-tests-for-antidepressants-cns-dose/feed/ 0 14344 Efficacy or Effectiveness https://www.gatewaypsychiatric.com/efficacy-or-effectiveness/ Sun, 26 Mar 2017 20:13:07 +0000 https://www.gatewaypsychiatric.com/?p=12601 What is the difference between efficacy and effectiveness? We tend to use these terms interchangeably in our posts on this site, but the two are different and the difference can be important. Efficacy refers to the power of a treatment to achieve a given outcome assuming that the patient is perfectly compliant and completes the treatment. Effectiveness addresses the more ...

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]]> 12601 Antidepressant Selection Based on Symptom Clusters https://www.gatewaypsychiatric.com/antidepressant-selection-based-symptom-clusters/ Fri, 03 Mar 2017 15:32:48 +0000 https://www.gatewaypsychiatric.com/?p=12483 Can we do a better job of antidepressant selection based on symptom clusters, analyzed using machine learning techniques? Perhaps so. And if so we will avoid a great deal of unnecessary suffering as people try one medication after another until the find the right medication or combination of medications to treat their depression. That is the premise behind an ambitious ...

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]]> 12483 Depression and Inflammation: Treatment Options https://www.gatewaypsychiatric.com/depression-inflammation-treatment-options/ Sat, 08 Oct 2016 21:22:33 +0000 https://www.gatewaypsychiatric.com/?p=11949 A host of conditions have been associated with mild to moderate levels of inflammation in the body. Depression is one of these. Elsewhere in this blog we have discussed the relationship between depression and inflammation, evidence that treatment with an antidepressant (escitalopram) reduces inflammation in depression, and talked about how exercise prevents depression. We have also noted that elevated levels of inflammation (simple ...

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]]> 11949 Mania and Depression Sequence https://www.gatewaypsychiatric.com/mania-and-depression-sequence/ Sun, 15 May 2016 13:03:05 +0000 https://www.gatewaypsychiatric.com/?p=10768 One of the key features of bipolar disorder that, in our experience, is most useful in predicting treatment response is the usual sequence of manic (or hypomanic) and depressive episodes. For years we have used the mnemonics MDI and DMI as ways of categorizing patients’ course. But we could not find the reference to that idea. We are indebted to ...

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