genetic testing Archives - Gateway Psychiatric

Genomind Genetic Testing by Mail

Peter Forster — Wed, 18 Mar 2020 19:17:55 +0000

We are happy to report that at least one of the services that we use for genetic testing, as part of our comprehensive evaluation for patients who had trouble finding an appropriate medication, is modifying the procedure for their tests so that we can order the test online and the test kit will be shipped directly to your home. Genomind ...

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Treatment Resources Index

Peter Forster — Sun, 24 Jun 2018 18:29:36 +0000

This weekend we have done some hard work behind the scenes creating a better treatment resources index to allow clinicians and patients to quickly access information about the array of services, online applications, clinical tests, pharmacogenetics tests, online courses and online CBT therapies that are provided at Gateway Psychiatric. There are so many tools in our toolbox that it can ...

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Genetic Tests for Antidepressants – CNS Dose

Peter Forster — Mon, 10 Jul 2017 02:25:56 +0000

About a year ago we reviewed the data on the use of genetic tests for antidepressants as well as other medications and identified three pharmacogenetic panels that seem to have research support: Genecept by Genomind, Genesight, and CNS Dose. Of these three we have been using Genecept and Genesight with some success but now we are happy to add to ...

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Antidepressant Response Linked to Norepinephrine Transporter Genotype

Peter Forster — Sun, 15 Jan 2017 03:06:41 +0000

A large study of patients treated with venlafaxine found that antidepressant response was linked to the norepinephrine transporter (NET) genotype. The study looked at response in a sample of 350 individuals over the age of 60 with severe depression (MADRS greater than or equal to 15) who were treated with venlafaxine up to a dose of 300 mg a day. ...

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Genesight – Genetic Testing to Predict Medication Response

Peter Forster — Wed, 24 Aug 2016 20:22:21 +0000

We have been using the Genecept Assay from Genomind for several years to help guide treatment selection in patients with either unusually high rates of side effects from medications or those who have failed multiple trials of medications. Although the test can be expensive, costing anywhere from a couple of hundred dollars to five hundred dollars or more, it is our experience ...

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Genetic Tests for Depression Updated 2023

Peter Forster — Sat, 11 Jun 2016 20:12:57 +0000

Do Genetic Tests Help? Are genetic tests for depression treatment worthwhile? Or is this an expensive technology that is not ready for routine use? Peter Roy-Byrne, writing in NEJM Journal Watch seems to say that they aren’t worth it. Although some clinicians may argue that such testing “can’t hurt and might help,” current psychopharmacological practice is complex, usually including combinations ...

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Genetics of bipolar disorder – update

Peter Forster — Sat, 30 Apr 2016 16:54:21 +0000

Unraveling the genetics of bipolar disorder has been a much more complicated task than anyone thought. Although the best estimates suggest that genetic factors account for the very high percentage of the risk of developing bipolar, with an estimated an estimated 0.7 to 0.8 heritability (Sullivan), it has been remarkably difficult to find genes with significant individual effects that are replicated ...

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Lithium and Genes

Peter Forster — Sun, 14 Feb 2016 20:15:58 +0000

Several studies have suggested that lithium response has a genetic component. Whether someone with bipolar will respond to treatment with lithium seems to be strongly associated with the presence or absence of a family history of response to the medication. A recent article in the Lancet reports the results of a genome-wide association study of lithium response in 2563 patients collected ...

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SAMe – S-adenosyl-methionine

Peter Forster — Sun, 08 Nov 2015 21:57:23 +0000

S-adenosylmethionine, or SAM-e for short, is one of the few nutritional supplements that has good clinical research to support its safety and effectiveness. Although SAM-e is used for many purposes, we are particularly interested in it as a compound that may have antidepressant properties. S-adenosylmethionine (SAMe) is involved in many reactions that involve methylating chemicals (transferring a methyl group to the ...

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ABCB1 Gene Predicts Antidepressant Response

Peter Forster — Tue, 31 Mar 2015 03:42:01 +0000

An article that will soon appear in the American Journal of Psychiatry suggests that it may be possible to predict who will respond to different antidepressants using a genetic test. The study looked at whether by testing for specific genetic variants of a protein involved in transporting drugs and other potentially toxic substances into and out of cells and across the blood ...

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