Rising Estrogen Levels Trigger Premenstrual Dysphoria

Peter ForsterGPS

New research suggests that rising estrogen and progesterone levels trigger premenstrual dysphoria symptoms. “Although the mechanisms underlying the mood-destabilizing effects of ovarian steroids in PMDD remain to be better characterized, as does the source of susceptibility to this trigger, our findings provide a new target for interventions,” Peter Schmidt, M.D., chief of the Section on Behavioral Endocrinology at the National …