Maternal SSRI Use and Autism

Peter Forster Physical Conditions and Health, Treatments of Depression

The CBS Evening News (4/18, story 9, 1:15, Pelley) reported, “Studies have shown that pregnant women who take antidepressants are more likely to have children with autism.” Newly published studies examine whether the medication is causing this. TIME (4/18, Park) reports that in two studies, investigators “found that other factors, including genes linked to mental illness, may be more strongly …

Delayed Circadian Rhythms

Peter Forster Insomnia, Insomnia Treatment, Psychobiology

Delayed circadian rhythms occur in a condition known as delayed sleep-wake phase disorder (DSWPD). This condition needs to be distinguished from disrupted circadian rhythms, a condition in which there are no strong circadian rhythms and therefore it’s hard for people to fall asleep, and when they do fall asleep they tend to have fragmented or light sleep. People with delayed …

Integrated Care

Peter Forster About GPS, Best Practices

We have a passion for providing the most effective treatment at Gateway and that passion is illustrated by the efforts that we make to ensure that we deliver integrated care. Integrated care is a very simple idea. In fact it is probably something that you expect your treatment providers are already delivering. It means that the different providers who are …

A Possible Cause of Bipolar Mania

Peter Forster Basic Science, Psychobiology

A recently published article by a group of Korean researchers hints at a possible cause of bipolar mania. The finding underlines the complex biology of bipolar disorder and perhaps why coming up with a biological mechanism for the dramatic shifts in behavior in bipolar has been so difficult. Background A number of pieces of evidence have suggested that phospholipase C signaling may …

Valbenazine for Tardive Dyskinesia

Peter Forster General

The FDA just approved a new drug, valbenazine, for tardive dyskinesia. Until now there have been few treatment options (vitamin E is sometimes helpful) and the most common choice patients and doctors had to make was to reduce the dose of the atypical antipsychotic that caused the tardive dyskinesia, or switch to another medication, possibly leading to worsened psychiatric symptoms. …

Ketamine Guidelines

Peter Forster Best Practices, Treatments of Depression

Ketamine guidelines have recently been published by American Psychiatric Association Council of Research Task Force on Novel Biomarkers and Treatments. They highlight what we know and what we don’t know about this treatment. What We Know “Several studies now provide evidence of ketamine hydrochloride’s ability to produce rapid and robust antidepressant effects in patients with mood and anxiety disorders that were previously resistant …

Motivational Interviewing for Change

Peter Forster Best Practices, Physical Conditions and Health

We were inspired, as we often are, by the discussion in the most recent session of our bipolar 101 group to add some more content on our webpage about motivational interviewing and motivational enhancement therapy. These techniques are so often relevant to the people that we work with because mood disorders are frequently associated with difficult problems such as substance …

Pill Minder and Information Source

Peter Forster Self Care

David Pogue recently reviewed 47 apps that can serve as a pill minder and information source and selected one that clearly outshone the others. But first, why is this important? This is some information from his article in Yahoo Finance… An estimated 187 million Americans (58%) are on at least one prescription drug. (Source: Network for Excellence in Health Innovation …

Efficacy or Effectiveness

Peter Forster Major Depression, Treatments of Depression

What is the difference between efficacy and effectiveness? We tend to use these terms interchangeably in our posts on this site, but the two are different and the difference can be important. Efficacy refers to the power of a treatment to achieve a given outcome assuming that the patient is perfectly compliant and completes the treatment. Effectiveness addresses the more …