Inflammation and Depression – Specific Symptom Cluster

adminBasic Science, Depression, Diagnosis, Major Depression, Physical Conditions and Health, Psychobiology Leave a Comment

A study of 15 population-based cohorts, totalling 56,351 individuals, suggests that there is a correlation between inflammation as measured by elevated  C-reactive protein (CRP) and interleukin-6 (IL-6) and a specific sub-group of symptoms of depression. The inflammation cluster consisted of four physical symptoms: changes in appetite, felt everything was an effort, loss of energy, sleep problems; and one cognitive symptom: little …

“Biggest Loser” Misunderstandings

Peter ForsterPhysical Conditions and Health, Self Care

Last week on most everybody in my practice who has ever struggled with weight loss came in talking about the widely reported results of a follow-up study to the TV show “Biggest Loser.” And almost everybody’s conclusion from the media coverage was that it seemed the media was suggesting that it was a waste of time trying to lose weight. Most …

Weight Gain with Atypical Antipsychotics – A Review of Strategies

Peter ForsterBipolar Treatment, Physical Conditions and Health

Many antipsychotics, especially some atypical or second generation antipsychotics, like olanzapine (Zyprexa) or quetiapine (Seroquel), cause significant weight gain, as well as insulin resistance (diabetes) and elevated lipids. What to do if the medication is helping (much more than alternatives) but the patient is developing these serious adverse effects? Two recent articles review the literature on strategies for managing these …