Below you'll find a list of all posts that have been categorized as “Major Depression”
A recent study published in the journal Nature Mental Health by researchers at the University of Cambridge revealed that attending in-person mindfulness courses has a lasting positive impact on mental health, even up to six months after completing the program. The study analyzed data from 13 randomized controlled trials, encompassing 2,371 participants. The researchers discovered that individuals who participated in …
A clinical trial conducted by researchers from UNSW Sydney has discovered that ketamine given as a subcutaneous shot effectively treats treatment-resistant depression. The findings, published in the journal the British Journal of Psychiatry, demonstrate that ketamine surpassed placebo in significantly reducing depressive symptoms. The trial involved 200 patients who had not responded to at least two other types of antidepressant …
A recent study published in the journal Psychopharmacology discovered that psilocybin-assisted treatment (PCT) effectively reduces symptoms of major depressive disorder (MDD) even after 12 months. Johns Hopkins University researchers conducted this study, closely monitoring and evaluating 24 participants who underwent PCT for MDD. These participants were evaluated at multiple intervals including baseline, 4 weeks, 12 weeks, and finally at the …
Depression is a common mental illness that affects millions of people worldwide. It can cause a wide range of symptoms, including sadness, fatigue, difficulty concentrating, and changes in appetite. Depression can also have a significant impact on a person’s quality of life. One way to treat depression is with medication. Antidepressants are a type of medication that can help to …
10 USEFUL* things you can do for suicide prevention *Spoiler: none of these things are about “fixing” a suicidal person. I’d like to apologize for missing the actual National Suicide Prevention Day, which was September 10, but, really, any day is a good day to talk about suicide prevention. Suicide prevention is not a matter of telling your distressed friend …
A study of 15 population-based cohorts, totalling 56,351 individuals, suggests that there is a correlation between inflammation as measured by elevated C-reactive protein (CRP) and interleukin-6 (IL-6) and a specific sub-group of symptoms of depression. The inflammation cluster consisted of four physical symptoms: changes in appetite, felt everything was an effort, loss of energy, sleep problems; and one cognitive symptom: little …
The COVID-19 pandemic appears to be associated with a higher burden of depressive symptoms than might have been predicted in comparison with earlier disasters and society-wide disruptive events, such as the September 11th attacks. Since April 2020, self-reported symptoms of depression have increased over the previous year, and remain high. A survey1 published in The Lancet Regional Health – Americas …
Suicide remains a sad mystery in many ways. Those left behind can never really know what was in their loved one’s mind at the last. We blame ourselves, and we deal with all the guilt, anger and grief that the act leaves behind, but we can never completely understand what leads someone to take their own life. Willa Goodfellow, in …
Three different findings associated with insulin resistance and pre-diabetes are predictive of developing depression according to a study published online from the American Journal of Psychiatry. Study Summary MedPage Today (9/23/2021) writes that, “Three surrogate measures for insulin resistance all showed a significant link with developing a major depressive disorder [MDD] over a nine-year follow-up period,” researchers concluded. The 601-participant study …
One of the questions that has bedevilled clinicians ever since the introduction of the first SSRI (Prozac, fluoxetine) is whether there is any relationship between SSRI doses and effectiveness. In other words, do higher doses result in greater effectiveness. I can recall about 20 years ago reading the first clinical trial looking at this question. It was an article published …
