Finger Stick Lab Tests

Finger Stick Lab Tests

Peter Forster GPS Update, Physical Conditions and Health, Testing Leave a Comment

Finger stick lab tests have the potential to significantly improve the quality of the care at Gateway Psychiatric. Regular monitoring of labs are an important part of good care for many of our patients, but some find it difficult to get labs done on time. A new technology from clinical laboratory provider OpAns may allow us to perform many of …

Predicting Lithium Response with Functional Brain Imaging

Predicting Lithium Response with Brain Imaging

Peter Forster Bipolar Treatment, Testing Leave a Comment

Predicting lithium response with brain imaging may be an option in the future if the preliminary results of a study published in 2017 are confirmed. Researchers from the University of Cincinnati used three tools to create a program that was remarkably successful at predicting which bipolar patients would respond to lithium. 20 first onset bipolar patients who received adequate trials …

Genetic Tests for Antidepressants – CNS Dose

Peter Forster Best Practices, GPS Update, Major Depression, Testing, Treatments of Depression Leave a Comment

About a year ago we reviewed the data on the use of genetic tests for antidepressants as well as other medications and identified three pharmacogenetic panels that seem to have research support: Genecept by Genomind, Genesight, and CNS Dose. Of these three we have been using Genecept and Genesight with some success but now we are happy to add to …

Functional Brain Imaging in Depression

Peter Forster Basic Science, Best Practices, Major Depression, Psychobiology, Testing, Treatments of Depression

Is there a role for functional brain imaging in depression? Many people seeking treatment are interested in the notion that the brain imaging, particularly imaging that looks at neural activity, might be useful in guiding treatment. Up until the last couple of years the answer to this question has always been that the role is primarily restricted to research settings …

Antidepressant Selection Based on Symptom Clusters

Peter Forster Best Practices, Major Depression, Testing

Can we do a better job of antidepressant selection based on symptom clusters, analyzed using machine learning techniques? Perhaps so. And if so we will avoid a great deal of unnecessary suffering as people try one medication after another until the find the right medication or combination of medications to treat their depression. That is the premise behind an ambitious …

Antidepressant Response Linked to Norepinephrine Transporter Genotype

Peter Forster Best Practices, Major Depression, Testing, Treatments of Depression

A large study of patients treated with venlafaxine found that antidepressant response was linked to the norepinephrine transporter (NET) genotype. The study looked at response in a sample of 350 individuals over the age of 60 with severe depression (MADRS greater than or equal to 15) who were treated with venlafaxine up to a dose of 300 mg a day. …

Neurocognitive Testing Online

Peter Forster Best Practices, Testing

Neurocognitive Testing Online Now Available Problems with memory, inattention, distractibility and cognitive function are common symptoms of mood and anxiety disorders. They may also be side effects of the medications used to treat those conditions. Or they may be a sign of some other condition that needs to be evaluated. How can these evaluated? A key part of a comprehensive assessment …

Genesight – Genetic Testing to Predict Medication Response

Peter Forster GPS Update, Psychobiology, Testing

We have been using the Genecept Assay from Genomind for several years to help guide treatment selection in patients with either unusually high rates of side effects from medications or those who have failed multiple trials of medications. Although the test can be expensive, costing anywhere from a couple of hundred dollars to five hundred dollars or more, it is our experience …

Genetic Tests for Depression Reviewed

Peter Forster Best Practices, Major Depression, Psychobiology, Testing

Are genetic tests for depression treatment worthwhile? Or is this an expensive technology that is not ready for routine use? Peter Roy-Byrne, writing in NEJM Journal Watch seems to say no. Although some clinicians may argue that such testing “can’t hurt and might help,” current psychopharmacological practice is complex, usually including combinations of multiple medications, and patients can have multiple …