A host of conditions have been associated with mild to moderate levels of inflammation in the body. Depression is one of these. Elsewhere in this blog we have discussed the relationship between depression and inflammation, evidence that treatment with an antidepressant (escitalopram) reduces inflammation in depression, and talked about how exercise prevents depression. We have also noted that elevated levels of inflammation (simple …
Naltrexone for Alcohol Use
Naltrexone is one of several new medications (the others are topirimate and acamprosate) that has been shown to reduce the risk of relapse in people with alcohol use disorders. But naltrexone is used relatively rarely for this purpose. A new study suggests that it may be possible to predict which patients are especially likely to respond to naltrexone treatment. The …
B Vitamins and Depression and Cognition
We ran across a Q&A from Consumer Lab on the role of B vitamins in depression which sparked us to update and expand this section of our page on nutritional supplements. ConsumerLab.com Answers Question: I’ve heard that having low B-12 or B-6 can cause depression. Is that true? Answer: Yes, being deficient in vitamin B-12 or B-6 can cause …
Antipsychotic Medications in Pregnancy
After decades during which the accepted medical dogma was that pregnant women should avoid all medications, the last 10 years have shown a significant increase in the quality of information available to help guide pregnant women in making decisions about which medications to continue taking during pregnancy. A recent editorial in the JAMA Psychiatry gives a sense of the context and …
Marijuana Use and Mental Health – 2022 Update
In the summer of 1996 proposition 216, California’s Compassionate Use Act, essentially legalized marijuana use with a prescription by a physician (“medical marijuana”) and in 2012, Colorado passed Amendment 64 (which legalized marijuana use in Colorado without any requirement for a prescription) – all of a sudden we were conducting a population based study of the impact of marijuana use …
Pregnancy Related Mental Health Information
I really like Anna Glezer’s website Mind Body Pregnancy as a resource for women who are pregnant, trying to get pregnant, or thinking about getting pregnant and wondering about the mental health issues they may face. I’ve highlighted three new articles on Mind Body Pregnancy and I encourage you to follow the links to the full articles and also to …
“Biggest Loser” Misunderstandings
Last week on most everybody in my practice who has ever struggled with weight loss came in talking about the widely reported results of a follow-up study to the TV show “Biggest Loser.” And almost everybody’s conclusion from the media coverage was that it seemed the media was suggesting that it was a waste of time trying to lose weight. Most …
Disability
Given the severity of mood and anxiety symptoms and some of the people we treat, we often deal with issues related to short-term or long-term work disability. In this post we will talk about common questions that come up when someone is impaired as the result of a psychiatric condition. Functional Assessment It often comes as a surprise to our …
Testosterone for Older Men
Does testosterone supplementation help older men with low testosterone improve their quality of life, mood and energy? Some of the “low T” advertisements on TV made it seem like the magic hormone that conquered aging. More recently the FDA has been expressing its concern about over-prescribing by, among other things, adding black box warnings on the labels of gel formulations of …
Pregnancy and Mental Health
This past week, a colleague at UCSF, Dr. Anna Glezer, wrote to let me know about a new patient-centered informational website she is launching focused on issues related to pregnancy and mental health. It’s called Mind Body Pregnancy, and she started it because in her reproductive psychiatry practice she was finding many patients asking similar questions. She wanted to reach beyond just those she is able to see in clinic and …